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Mechanism of action in CBT (MAC): methods of a multi-center randomized controlled trial in 369 patients with panic disorder and agoraphobia
2013-02-22
[Electronic ed.]
4519974-7
Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
prv
Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, Dresden
Fakultät Mathematik und Naturwissenschaften
Professur für Klinische Psychologie und Psychotherapie
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Cognitive behavioral therapy (CBT) is efficacious for panic disorder with agoraphobia (PD/A). Nevertheless, the active ingredients of treatment and the mechanisms through which CBT achieves its effects remain largely unknown. The mechanisms of action in CBT (MAC) study was established to investigate these questions in 369 patients diagnosed with PD/A. The MAC study utilized a multi-center, randomized controlled design, with two active treatment conditions in which the administration of exposure was varied, and a wait-list control group. The special feature of MAC is the way in which imbedded experimental, psychophysiological, and neurobiological paradigms were included to elucidate therapeutic and psychopathological processes. This paper describes the aims and goals of the MAC study and the methods utilized to achieve them. All aspects of the research design (e.g., assessments, treatment, experimental procedures) were implemented so as to facilitate the detection of active therapeutic components, and the mediators and moderators of therapeutic change. To this end, clinical, behavioral, physiological, experimental, and genetic data were collected and will be integrated.
150
CU 3100, CU 8500
Panikstörung, Agoraphobie, kognitiv-behaviorale Therapie, Konfrontationstherapie, Mechanismen, Methoden
Panic disorder, Agoraphobia, CBT, Exposure therapy, Mechanisms, Methods
urn:nbn:de:bsz:14-qucosa-106614
380776553
10.1007/s00406-009-0065-6
Technische Universität Dresden
pbl
Technische Universität Dresden, Dresden
Andrew T.
Gloster
aut
Hans-Ulrich
Wittchen
aut
Franziska
Einsle
aut
Michael
Höfler
aut
Thomas
Lang
aut
Sylvia
Helbig-Lang
aut
Thomas
Fydrich
aut
Lydia
Fehm
aut
Alfons O.
Hamm
aut
Jan
Richter
aut
Georg W.
Alpers
aut
Alexander L.
Gerlach
aut
Andreas
Ströhle
aut
Tilo
Kircher
aut
Jürgen
Deckert
aut
Peter
Zwanzger
aut
Volker
Arolt
aut
eng
2009
http://dx.doi.org/10.1007/s00406-009-0065-6
Link zur publizierten Version des Artikels, der in der Zeitschrift "European Archives of Psychiatry and Clinical Neuroscience" des Springer-Verlags erschienen ist.
European Archives of Psychiatry and Clinical Neuroscience, Bd. 259 (2009), Nr. 2 Supplement, S. 155-166, ISSN: 0940-1334 , EISSN: 1433-8491
born digital
Sara Maget
sara.maget@slub-dresden.de
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